Liver Cancer Test
How Prevalent is Liver Cancer in America?
Liver cancer is one of the most common cancers among men and women, however the ability to confirm the presence of cancer early strongly affects the survival rate.
In 2018, it is estimated that 42,000 individuals in the United States will be diagnosed with liver cancer and 30,000 individuals will die of this cancer. The incidence of liver cancer has more than tripled since 1980. This information can be found on The American Cancer Society’s website
The average 5-year survival rate for liver cancer is around 18%. This is highly affected by the stage in which the cancer is identified. For individuals diagnosed with an early stage liver cancer, the 5-year survival rate is 31%. If individuals are diagnosed with liver cancer after local metastasis, the 5-year survival rate drops to 11%, or with distant metastasis the rate drops to 3%. Statistics adapted from the American Cancer Society’s (ACS) publication, Cancer Facts & Figures 2018, and the ACS website.
A new liver cancer test, the IvyGene Liver test, is a simple blood test that uses advanced DNA sequencing methods to test for liver cancer and confirm the presence of liver cancer, as early as stage 1.
What are the symptoms of liver cancer?
There are certain factors that increase a person’s risk of developing liver cancer:
- Weight loss
- Loss of appetite
- Nausea and vomiting
- Abdominal swelling
- White, chalky stools
What are the risk factors for developing liver cancer?
Because Liver cancer doesn’t display symptoms early on, the development of a blood test provides an effective way to confirm it early. When symptoms do occur, they may include:
- Cirrhosis — Chronic alcohol abuse and hepatitis can cause this irreversible condition that causes scar tissue to form in the liver and increases the chances of developing liver cancer.
- Chronic infection with hepatitis — Chronic infection with hepatitis B and hepatitis C increases liver cancer risks.
- Inherited diseases such as Wilson’s disease
- Nonalcoholic fatty liver disease
- Exposure to aflatoxins — Aflatoxins are poisons produced by molds growing on crops that aren’t stored correctly.
- Excessive alcohol consumption — Consuming more than moderate amounts of alcohol daily over years can damage the liver and increase the risk for liver cancer.
How is liver cancer diagnosed?
- Liquid Biopsy — The IvyGene Liver test is a blood test that can confirm the presence of liver cancer, as early as stage 1.
- Imaging tests — Ultrasound, computerized tomography (CT) scans, and magnetic resonance imaging are used to detect liver cancer.
- Biopsy of liver tissue — During a liver biopsy, a doctor inserts a thin needle through your skin into the liver to obtain a tissue sample. The sample is then examined to look for cancer cells specific to liver cancer.
Why use the IvyGene Liver test?
The IvyGene Liver test is a highly sensitive and specific blood test that confirms the presence of liver cancer, as early as stage 1. This blood test provides a highly accurate, non-invasive complimentary tool to the current standards of care.
Current liver cancer tests available on the market today, do not offer a potent combination of high sensitivity and specificity, many only have one or the other. The IvyGene Liver test provides patients with cirrhosis or hepatitis a great tool to confirm the presence of liver cancer, before it becomes life threatening.
With a low false negative rate, patients and physicians may rely on the IvyGene Liver test for a more accurate confirmation of cancer presence and streamline the diagnosis process.
The test currently meets FDA requirements for a Laboratory Developed Test (LDT). Our laboratory is CLIA Registered (Clinical Laboratory Improvement Amendments) and CAP Accredited (College of American Pathologists).